Category: ICP Research

Concerns with 2019 study of efficacy of Ursodeoxycholic Acid

CONCERNS WITH 2019 STUDY OF EFFICACY OF URSODEOXYCHOLIC ACID

A study published in the Lancet in August of 2019 compared Ursodeoxycholic Acid to placebo in women with intrahepatic cholestasis of pregnancy. This study failed to find a significant difference between the study group and the control group. Overall, the study was well-designed. However, there was one important issue that may have profoundly impacted the… Read more »

Interpretations of the 2019 ICP meta-analysis

INTERPRETATIONS OF THE 2019 ICP META-ANALYSIS

In February of 2019, a groundbreaking study was published regarding Intrahepatic Cholestasis of Pregnancy (ICP), which found that under modern management practices the risk of stillbirth is not higher until bile acids reach 100 μmol/L. The study was a fantastic example of international cooperation into research of a rare disease. Unfortunately, confusion about what this… Read more »